Vitiligo is a health condition that causes depigmented patches of the skin. A patient develops vitiligo when the immune system starts attacking melanocytes or the melanin-producing cells. While there is no cure for vitiligo, doctors generally recommend undergoing certain procedures for repigmentation of the skin to those who want to deal with the impact of the condition. Opzelura (ruxolitinib) is an FDA-approved topical repigmentation cream that can help treat vitiligo.

Vitiligo progression
Vitiligo is present in more than 1% of the world’s population. In most patients, the patches become apparent before the age of 25. But, the condition can occur in patients of all ages and genders. Moreover, people with autoimmune conditions like anemia, diabetes, rheumatoid arthritis, lupus, thyroid, psoriasis, and Addison’s disease are at a higher risk of developing vitiligo. The condition begins with a few patches or macules before starting to spread to the rest of the body. Hands, feet, forearms, and face are common parts of the body that first show the presence of vitiligo. The condition can also impact the patient’s mucous membranes, eyes, and inner ears.

How Opzelura works
For treating vitiligo, doctors can recommend using Opzelura—a prescription cream that helps restore the pigments in the macules and patches. It is the first treatment option approved by the FDA for vitiligo treatment. The ointment contains ruxolitinib as a main ingredient and works by slowing down or decreasing the rate of destruction of melanocytes. It is believed that this change can help patients restore their skin pigmentation throughout usage.

Uses
The cream can be used in patients with non-segmental vitiligo aged 12 years or above. Patients can apply the product themselves without needing assistance or precautions, but it can be used on up to 10% of the body’s skin. It can also be applied to sensitive areas like the eyes, genitals, and the mouth.

Patients with widespread vitiligo might need to discuss with their doctor regarding the areas they should target. When discussing the use of the product with the doctor, make sure to learn about its usage and effects. Different patients will need different treatment strategies depending on the ongoing plans they are following. The cream can be applied in a thin layer on the affected area for the prescribed amount of time by the doctor.

Usage suggestion
It is suggested that patients limit the time they spend in the sun when using Opzelura cream. Alternatively, some patients can receive case-specific instructions about using the treatment option and must follow the doctor’s advice. Healthcare professionals can draw up a recommended treatment plan for patients.

It is also important for patients to check their eligibility for a co-pay to save on their purchase of Opzelura cream. Opzelura On Trac Patient Support is an initiative by the brand to help patients obtain the cream, stay on track with treatment, and receive any assistance needed.